Assisted Reproductive Technologies (ART) refers to fertility treatments and procedures that can help with difficulty or inability to conceive children. ART techniques involve the manipulation of eggs, sperm, or embryos to increase the chances of a successful pregnancy.
Infertility is when people cannot conceive after a period of regular sex without the use of birth control. The evidence suggests that roughly
According to the CDC,
In this article, we’ll discuss some of the different types of ART, including their success rates, benefits, risks, costs, and the ethics of the technology.
People considering ART will often discuss options with a healthcare professional and may need a consultation with a fertility specialist.
While people primarily use ART to treat infertility, others may use it for genetic purposes or to prevent pregnancy complications. Some people may also talk about ART as a treatment for fertility or assisted reproduction.
It’s possible hard for many people to access fertility services such as antiretroviral therapy because of its high cost and limited coverage by private insurance and Medicaid.
There are Several types ART procedures that involve different techniques and reproductive cells. A doctor can advise which ART will be most appropriate depending on the circumstances. The most common type is in vitro fertilization (IVF).
IVF involves a doctor who extracts the eggs and fertilizes them in a special laboratory. Specialists can combine this with embryo transfer (IVF-ET) and transfer the resulting embryos to a person’s uterus. The Society for Assisted Reproductive Technology states that IVF-ET represents 99% ART procedures.
The Centers for Disease Control and Prevention (CDC) lists the Success rate 2018 IVF treatments for the retrieval of an egg from people using their own eggs, such as:
- 52% for people aged 35 or under
- 38.1% for 35-37 year olds
- 23.5% for 38-40 year olds
- 7.6% for those over 40
A person can also use a tool called a
It may take more than one IVF cycle to become pregnant, and some people may not conceive at all with IVF. The benefits of IVF are an increased chance of fertilization and pregnancy. Potential complications can include:
The National Conference of State Legislatures lists the average cost of a single IVF cycle as $ 12,000 to $ 17,000.
Click here to learn more about IVF.
Some methods of ART are similar to IVF but use laparoscopic surgery to deliver gametes directly into the fallopian tube. Some people may choose this method for religious reasons, or their insurance may only cover this type of ART.
Like other forms of ART, the risk of multiple pregnancy is increased. In addition, due to laparoscopy, there is a risk of complications from the surgery, such as infection, organ puncture, or side effects of anesthesia. Intrafallopian transfers are generally more expensive than IVF.
Due to the higher costs and risks of this type of ART, specialists rarely use these procedures. As such, there isn’t a lot of data available on their success rates.
The types include:
- Intrafallopian gamete transfer (GIFT): The GIFT involves collecting eggs and sperm in a tube before a doctor places the gametes directly into the fallopian tubes using laparoscopic surgery. Since there is no IVF procedure, a person does not have to choose which embryo to transfer.
- Zygote intrafallopian transfer (ZIFT): ZIFT is a combination of IVF and GIFT. Specialists stimulate and remove the eggs using IVF methods and mix the eggs with sperm in the lab before putting the fertilized eggs or zygotes back into the fallopian tubes. One of the benefits of ZIFT is that it can help people with damaged fallopian tubes or severe infertility problems get pregnant.
- Tubal transfer at the pronuclear stage (PROST): PROST is similar to ZIFT but involves the transfer of a fertilized egg into the fallopian tube before cell division occurs.
Frozen embryo transfer
Frozen embryo transfer (FET) has become increasingly common in the United States. This involves thawing embryos previously frozen by IVF and inserting them into a person’s uterus. A 2017 study found that 52% of people who have had FET have had ongoing pregnancies.
According to UK Authority of Human Fertilization and Embryology, FET is as safe as using fresh embryos in processing. However, some evidence suggests an increased risk of preterm delivery with FET. Another possible risk of FET is that not all frozen embryos survive the thawing process.
The estimated cost of FET varies but can go up to $ 6,000.
Intracytoplasmic sperm injection
Intracytoplasmic sperm injection (ICSI) is a procedure that specialists can perform alongside IVF to help fertilize an egg. An embryologist, or embryo specialist, uses a small needle to inject a single sperm directly into the center of an egg.
ICSI fertilizes between 50-80% of eggs. The success rate of ICSI is similar to that of IVF, and it may be a efficient method ART for people with sperm-related infertility. ICSI is usually a complementary procedure to IVF, so it will be more expensive than IVF alone.
Things to consider about ICSI include the following:
- The procedure may damage some or all of the eggs.
- The egg may not become an embryo even after receiving a sperm injection.
- If a person becomes pregnant naturally, there is a 1.5 to 3% risk of the baby having a major birth defect. However, the underlying infertility, rather than the treatment, may be the cause of the birth defect.
Evidence suggests that
- It can work when IVF has repeatedly failed.
- This can help avoid passing on specific conditions.
- It can help a person who is producing healthy eggs but has had difficulty carrying a pregnancy to term.
- It can help those who have difficulty producing an egg or sperm.
Depending on the type of people chosen, third-party ART can be very expensive. Sperm donation is usually the cheapest option, costing around $ 1,000 per bottle.
The cost of other options may vary for a single vial, and many cycles will require multiple vials. The estimated costs are:
Preparing for antiretroviral therapy includes practicing behaviors that
It could also involve regular exercise and stopping smoking. Once ART is successful,
Many aspects of ART raise
- Does an individual or a couple need ART?
- Who owns the stored gametes and embryos?
- Is it ethical for people to donate eggs to a clinic for free or low cost treatment?
- How do a person’s religious beliefs align with different ART procedures?
- Should there be age limits for ART?
- Do children born by donation of gametes have the right to know their conception and their genetic parents?
- Are all requests for antiretroviral therapy treated the same, regardless of relationship status or sexual orientation?
- Is it ethical to use frozen embryos or sperm from a deceased person?
There are no simple answers to the ethical questions of ART. The American Society for Reproductive Medicine has a collection of ethics documents available here.
There are many types of ART available to treat infertility. ART success rates vary depending on the type of ART chosen and factors such as a person’s age and health.
A specialist will suggest ART based on an individual’s or couple’s preferences and type of infertility while weighing the risks, benefits, and costs.